ERGOLINES Meaning and
Definition
-
Ergolines are a class of organic compounds that possess a common skeleton structure called ergoline, which is a tricyclic molecule consisting of two rings fused to a six-membered ring. This class of compounds is known for its diverse pharmacological properties and is widely studied in organic chemistry and medicinal science.
Ergolines exhibit a wide range of biological activities, including the ability to bind to and activate various receptors in the central nervous system. They are often used as the basis for the synthesis of drugs targeting a variety of conditions, such as migraines, Parkinson's disease, and psychiatric disorders.
The structural versatility of ergolines allows for the modification of different positions on the tricyclic ring system, leading to the development of various derivatives with unique properties and improved pharmacokinetic profiles. This has contributed to the development of several important pharmaceutical agents belonging to different therapeutic classes, such as dopamine agonists, serotonin receptor agonists, and adrenergic receptor blockers.
In addition to their pharmaceutical relevance, ergolines also exhibit notable biological activities in other areas. Some derivatives have been shown to possess antimicrobial, antifungal, and antiviral properties, making them of interest in the development of novel therapeutic agents.
Overall, the study of ergolines encompasses both their synthesis and their biological activities, with continuous research efforts focused on exploring their potential applications in medicine and related fields.
Common Misspellings for ERGOLINES
Etymology of ERGOLINES
The word "Ergolines" is derived from the chemical name "ergoline". The term "ergoline" was first coined by Swiss chemist Albert Hofmann in 1958. It was derived from the word "ergot", a fungus that affects certain grains and produces alkaloids with physiological effects on humans and animals. Ergoline compounds, including ergot alkaloids, have been extensively studied for their psychoactive and physiological properties, particularly in relation to hallucinogenic and vasoconstrictive effects. The suffix "-ine" in ergolines represents the generic ending for alkaloids.
Infographic
Add the infographic to your website:
