CXCR PROTEIN Meaning and
Definition
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The CXCR protein, also known as C-X-C chemokine receptor type 4, is a cell surface receptor belonging to the G-protein coupled receptor (GPCR) family. This protein is encoded by the CXCR4 gene and is primarily expressed on the surface of immune cells, such as T cells, B cells, and monocytes.
CXCR is a chemokine receptor that specifically binds to chemokine ligand 12 (CXCL12), a chemokine also called stromal cell-derived factor 1 (SDF-1). This interaction between CXCR and CXCL12 plays a crucial role in regulating various physiological and pathological processes, including immune system modulation, leukocyte trafficking, and hematopoiesis.
Upon ligand binding, the activation of CXCR triggers a signal transduction cascade within the cell, leading to the modulation of intracellular signaling pathways. These signaling pathways regulate a wide range of cellular processes, such as migration, adhesion, and survival.
Dysregulation of CXCR signaling has been implicated in the pathogenesis of several diseases, including cancer, HIV infection, and autoimmune disorders. Therefore, CXCR has emerged as a potential therapeutic target for the development of drugs aimed at modulating immune responses, inhibiting cancer metastasis, and preventing HIV entry into cells.
Further research and understanding of the CXCR protein and its associated signaling pathways may provide valuable insights into the development of novel therapeutic strategies for various diseases.
Common Misspellings for CXCR PROTEIN
- xxcr protein
- vxcr protein
- fxcr protein
- dxcr protein
- czcr protein
- cccr protein
- cdcr protein
- cscr protein
- cxxr protein
- cxvr protein
- cxfr protein
- cxdr protein
- cxce protein
- cxcd protein
- cxcf protein
- cxct protein
- cxc5 protein
- cxc4 protein
- cxcr orotein
- cxcr lrotein
Etymology of CXCR PROTEIN
The etymology of the word "CXCR protein" is as follows:
1. CXCR: The term "CXCR" stands for CXC chemokine receptor. Chemokines are a type of signaling protein involved in immune response and cell migration. The "CXC" designation refers to a specific class of chemokines. The "R" denotes receptor, which is a protein molecule located on the surface of cells that binds to chemokines and initiates a cellular response.
2. Protein: The term "protein" originated from the French word "protéine" in the early 19th century, which was derived from the Greek word "prōteios" meaning "primary" or "of the first rank". It was initially used to describe a class of nitrogenous organic compounds found in living organisms.
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